Histamine containing endocrine cells in the human stomach.
نویسندگان
چکیده
Histamine and chromogranin A-immunoreactive cells were studied in the mucosa of the human stomach. Cells reacting to both histamine and chromogranin A-antibodies (histamine containing endocrine cells), were demonstrated by double immunostaining and found to be restricted to the oxyntic mucosa. Histamine containing cells that did not stain with chromogranin A-antibodies were numerous throughout the stomach. Of the histamine immunoreactive cells in the oxyntic gland area 22% reacted with antibodies against chromogranin A. Histamine containing endocrine cells constituted 44% of the total number of endocrine cells in the oxyntic mucosa. These findings suggest that the histamine containing endocrine cells in the human stomach are identical with the so called enterochromaffin like cells.
منابع مشابه
Distribution and relative frequency of immunohistochemically detected endocrine cells in the stomach of New Zealand White rabbit (Oryctolagus cuniculus)
Background: Gastrointestinal (GI) endocrine cells produce many GI hormones that perform various physiological functions of the digestive system. Aims: We aimed to investigate the presence and distribution of immunoreactive (IR) endocrine cells to glucagon, somatostatin, cholecystokinin-8 (CCK-8), serotonin, secretin and histamine in the stomach of adult male Ne...
متن کاملImmunohistochemical study of the endocrine cells in the stomach and pyloric caeca of the mountain trout, Salmo trutta macrostigma
The endocrine cells of Salmo trutta macrostigma stomach and pyloric caeca have been investigated using immunohistochemical techniques. 8 antisera were tested and 6 of them were detected in the endocrine cells serotonin, somatostatin, substance P, galanin, CCK and neuropeptide Y. These immunoreactive cells are described for the first time in the stomach and pyloric caeaca of Salmo trutta macros...
متن کاملHistamine-containing peripheral neuronal and endocrine systems.
An immunohistochemical method was developed to detect histamine in tissues. The aim of this study was to reveal the cellular stores of histamine in the gastrointestinal tract, pituitary, and adrenal gland. Histamine-containing nerve fibers were found in both rat and guinea pig gut. The origin of at least some of these fibers in the rat ileum was the submucous ganglion cell layer. In the rat sto...
متن کاملImmunohistochemical study of the endocrine cells in the stomach and pyloric caeca of the mountain trout, Salmo trutta macrostigma
The endocrine cells of Salmo trutta macrostigma stomach and pyloric caeca have been investigated using immunohistochemical techniques. 8 antisera were tested and 6 of them were detected in the endocrine cells serotonin, somatostatin, substance P, galanin, CCK and neuropeptide Y. These immunoreactive cells are described for the first time in the stomach and pyloric caeaca of Salmo trut...
متن کاملRegional and mucosal distributions of some intestinal immunoreactive endocrine cells in New Zealand white rabbit (Oryctolagus cuniculus L.)
The aim of this study was to detect the regional and mucosal distribution of endocrine cells that secrete gulcagon, somatostatin, Chyholecystokinin-8 (CCK-8), serotonin, secretin, substance P (SP) and histamine in the small and large intestine of New Zealand white rabbit (Oryctolagus cuniculus L.) using immunohistochemical peroxidase-antiperoxidase (PAP) method. It was found that most of the im...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Gut
دوره 31 4 شماره
صفحات -
تاریخ انتشار 1990